Description
When collagen fi bers deteriorate, peptides signal the fi broblasts to produce additional collagen. Neuropeptides, however, work differently. Within the skin, they diffuse the constant communication between the nerve and the muscle, inhibiting the contractions that can cause wrinkles to form. Growth factors are bioactives that trigger responses and processes within the body. They are naturally occurring, and can stimulate cellular growth, proliferation, healing, and cellular differentiation. In the skin, growth factors are secreted by all of the cell types located in the epidermis and the dermis, including keratinocytes, fi broblasts, and melanocytes. The growth factors that the skin produces naturally are responsible for stimulating the biochemical pathways that enable the skin to heal and protect itself, as well as ensure that it is functioning optimally.